Sentence examples for active destruction from inspiring English sources

This activates Disheveled (Dvl), which then inhibits the constitutively active destruction complex consisting of Axin, GSK3β and APC.

Irrelevant to their size, all clot types involve the active destruction of blood cells, particularly of morula cells that are activated through the expression of the phenoloxidase system (PO; 12), not found in vertebrates.

It is willful neglect, including the active destruction of records and the failure to comply with court orders.

The TOR pathway, in turn, promotes protein production and inhibits the active destruction of parts of cells that are no longer needed.

Recently, it was reported that phosphorylation of Axin by CKI may also improve its association with GSK3 and leads to a more active "destruction complex", while protein phosphatase 1 (PP1) interacts with, and dephosphorylates Axin, reversing the effect conferred by CKI and hence contributing to the activation of Wnt signaling (Luo et al., 2007).

The key to our image of a clean and starched history is largely a result of a mixture of active destruction and strategic ignorance.

Active myelin destruction was associated with activated microglia (Fig.  1h), containing myelin degradation products (Fig.  1l) and expressing the phagocytosis associated marker CD68 (Fig.  1i) and NADPH oxidase (Fig.  1m).

Immunopathological characterization of brain tissue from our clinical case allowed us to identify deposition of activated complement protein at sites of active myelin destruction in active L-III indicating demyelinating pattern II. 4 Consistent with this pattern, antibody-producing plasma cells were present in this lesion, but also in the other two less active lesions (L-I and II).

The released insulin was proved to remain active without destruction of the tertiary structure.

Patterns (IP) I and II are characterized by a marked T cell/macrophage-associated demyelination, with (IP II) or without (IP I) additional immunoglobulin and complement depositions at sites of active myelin destruction, respectively.

Taken together, we conclude that while the constitutively active Axin1 destruction complex destabilizes cytoplasmic β-catenin, Nkd1 does not appear to antagonize the Wnt pathway at this level, arguing that Nkd1 may instead be acting downstream of stabilized cytoplasmic β-catenin.