The phrase "active concentration" is correct and usable in written English.
It can be used to describe a state of focused mental engagement or attention on a specific task or subject.
Example: "To achieve optimal performance, one must maintain active concentration during challenging tasks."
Alternatives: "focused attention" or "intense focus".
Interestingly, the impact of PI3K inhibition was specific to BAR activation induced by dual inhibition of DHFR and GSK3, as wortmannin has little impact on BAR activation induced by an active concentration of BIO (Figure 6, blue bars).
Pure NE of known activity was diluted to an active concentration of 100nM with buffer (50 mM Hepes, pH 7.4, 150 mM NaCl, 0.05% Igepal CA-630 (v/v)).
From the linear portion of the slope, the half time (t½) of the reaction was calculated using the formula: t 1 2 = y intercept / slope Kass was calculated using the equation [ 12]; K ass = Concentration of NE × t 1 2 ‒ 1 Pure PR3 of known activity was diluted to an active concentration of 400 nM.
This phenotype was due to the amplification of the MDR-1 gene locus that encodes Pgp, a specific membrane transporter protein responsible for the expulsion of many drugs, restricting their active concentration within cells and thus cytotoxic activity.
Possibly, the phosphorylation of splicing regulators, mediated by MBNL142 43 overexpression and SFK activation, allows the cells to lower temporarily their active concentration, further aggravating the DM spliceopathy, resulting from the MBNL1 sequestration into the nuclear foci.
None of these selected derivatives showed significant acute toxicity against MRC-5 cells or early signs of genotoxicity in the Vitotox™ assay at the active concentration range.
Our data from real-time PCR and microarray analyses indicated that expression of the csgBAC operon was decreased to a greater degree than that of the csgDEFG operon upon deletion of dnaK (Fig. 2b, c), suggesting that the CsgD levels fell below their active concentration and/or that CsgD quality was compromised in the ΔdnaK strain.
The fact that BPA-induced differentiation is not inhibited in the presence of an active concentration of the GR antagonist RU486 (Figures 4c and d) argues that the BPA effect is not mediated through activation of the GR in this model system.
The final filter was to select compounds with an active concentration of 1.0 μM or below.
Actually, synergistic action can exist in herbal medicine, decreasing active concentration of pure compound [38, 45].
Active concentration of DOX was 16.7 % w/w from 3.34 mg/ml to 16.3 μg/ml.
