Sentence examples for active anticancer from inspiring English sources
The clinical use of doxorubicin, a highly active anticancer drug, is limited by its severe cardiotoxic side effects.
Evaluation of the synthesized compounds against HEPG2 hepatocellular carcinoma cells in vitro identified compounds 5b, 6b and 10 13b as most active anticancer agents with IC50 equal to 0.12, 0.29, 0.58, 0.44, 0.42 and 0.66 µM, respectively.
In the future, we are planning in vivo investigations of these new active anticancer agents to better elucidate active mechanisms at the cellular level and thus benefit the development of anticancer therapies.
We have synthesized graphene oxide using improved Hummer's method in order to explore the potential use of the resulting graphene oxide as a nanocarrier for an active anticancer agent, chlorogenic acid (CA).
The highly active anticancer compound 11h exhibited obvious ROS elevation and excellent in vivo antitumor potency with suppressed tumor growth by 48.58% at the dose of 2 mg/kg.
In this study, we developed a novel system in which antitumor prodrug is inactivated by the modification with the functional group and reduces the adverse effect to normal tissues which are generally present under normoxia condition but releases active anticancer drug under hypoxic condition.
5-FU is an S-phase-active anticancer agent, and it has no activity when cells are in G0 or G1[3].
Recent studies support that botanical endophytic microbes synthesize active antiviral, anticancer, antioxidant and immunosuppressive compounds [58].
These figures indicate that these were indeed the patients with malignancies for which no effective standard treatments exist, or alternatively these patients were accrued into phase I trials containing at least one active approved anticancer agent.
Through diverse molecular pathways and biological processes, MPA has an active role in anticancer activities [ 48].
While a vast number of metal complexes have been synthesized and reported to be promising and potent in vitro anticancer active compounds, fewer have shown efficacy in in vivo models.
