The phrase "activation up" is not standard in written English and may be unclear without context.
It could potentially be used in a technical or gaming context to indicate that a system or feature is being activated or turned on.
Example: "Please ensure that the activation up process is completed before proceeding to the next step."
Alternatives: "activation initiated" or "activation enabled".
Luciferase activity in flies expressing cec NF-κB reporter demonstrated elevated levels of NF-κB activation up to 72 h in the infected with antibiotics group, while activity in the sham group was not upregulated after pricking (p < 0.0001) (Fig. 2b).
Toward this, we utilized split-Cas9 systems to develop a modular adeno-associated viral (AAV) vector platform for CRISPR-Cas9 delivery to enable the full spectrum of targeted in situ gene regulation functionalities, demonstrating robust transcriptional repression (up to 80%) and activation (up to 6-fold) of target genes in cell culture and mice.
Our results show that cells pass from a state of high responsiveness to N-pathway activation (up to 50%) during the first 60 minutes of life to a low, no null, responsiveness state (under 50%) with a period of transition around 60 to 75 minutes after birth.
Superantigens of specific bacteria (Streptococcus, Staphylococcus) and viruses (Epstein Barr virus (EBV)) bypass the processing of antigen-presenting cells through directly binding to MHC II molecule T-cell receptors outside the conventional antigen-specific variable chains, initiating massive T-cell activation (up to 20% of total).
Injection of TGFbeta1 alone resulted in a robust activation (up to 40-fold) of all three chondrogenic genes in the meniscus/synovium (Table 3 Acute), which is in marked contrast to the minimal effect of TGFbeta1 on chondrogenic genes in cartilage/subchondral bone (Table 1 Acute).
Enter, on white charger, Mr Emollient Whittingdale, offering to stick clause activation up his jumper for a while and maybe for ever as long as the Independent Press Standards Organisation makes further progress (which, trialling arbitration techniques and appointing an independent auditor of its performance, Ipso is certainly striving to do).
PolyADP-ribose polymerase-1 activation up-regulated ERK-activity, inducing Elk1 phosphorylation and thereby core histone H4 acetylation due to histone acetyltransferase (HAT) activity (Cohen-Armon et al, 2007).
Statins stimulate P450 enzymes which generate PPAR-activating eicosanoids (83, 84) and via PPAR activation up-regulate LXR, ABCA1, and ABCG1 genes in cholesterol-loaded macrophages and hepatocytes, and promote cholesterol efflux to apo AI and HDL (79).
The enhanced cytotoxicity of ATO + bortezomib was associated with augmented STAT3 inhibition and JNK activation, up-regulation of Bim, p21, p27, p53 as well as down-regulation of Bcl-2.
T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+.
TLR activation up-regulates the expression of Vitamin D receptor (VDR) and Vitamin D-1-hydroxylase, leading to the induction of a peptide, namely cathelicidin, which can kill intracellular Mtb (Liu et al., 2006).
