Sentence examples for activation the release of from inspiring English sources

The complex pathophysiology of these disease processes is associated with immune system activation, the release of cytokines and chemokines, and alterations in cell populations.

Activation of mast cells via FcεRI causes the immediate release of pre-formed mediators, the production of newly formed lipid mediators and 8 to 12 hours after activation the release of newly synthesized cytokines and growth factors [7], [8].

These results demonstrated that Bid could upregulate Bak activation; the release of AIF and endoG; and subsequently apoptosis.

Indeed, KCN treatment in HeLa cells facilitated Bax activation, the release of cytochrome c and caspase-9 activation upon H2O2 treatment.

In contrast, the enzymatically inactive CerS6R131A variant, CerS1 or CerS3 failed to induce Bax activation, the release of cytochrome c or activation of caspase-9.

The resulting inflammatory state is accompanied by maternal leukocyte activation, the release of cytokines from immune cells and uteroplacental tissues, and endothelial cell activation, as well as immune coagulation interactions.

Previous studies have demonstrated that activated Bid can mediate Bak activation and the release of AIF and endoG.

Neuronal activation triggers the release of neuropeptides and neurotransmitters, thereby further activating mast cells.

We observed that hsFlt3L can generate DCs from peripheral blood precursors; activation stimulates the release of Th1 cytokines and reduces the phagocytic activity of DCs.

One of the benefits of anticancer therapy is the induction of apoptosis by the kinases activation and the release of cytochrome c into the cytosol, which activates caspases [ 15, 16].

Several studies suggested that inhibition of STAT3 activation promotes the release of proinflammatory cytokines, while a mutant having constitutively active STAT3 in fibroblasts suppressed the LPS induced pro-inflammatory response [ 70, 83– 83].