The phrase "activation the release" is not correct in written English.
It seems to be a mix-up of words and lacks proper grammatical structure.
Example: "The activation of the release mechanism is crucial for the device to function properly."
Alternatives: "initiation of the release" or "triggering the release".
The complex pathophysiology of these disease processes is associated with immune system activation, the release of cytokines and chemokines, and alterations in cell populations.
Activation of mast cells via FcεRI causes the immediate release of pre-formed mediators, the production of newly formed lipid mediators and 8 to 12 hours after activation the release of newly synthesized cytokines and growth factors [7], [8].
These results demonstrated that Bid could upregulate Bak activation; the release of AIF and endoG; and subsequently apoptosis.
In contrast, the enzymatically inactive CerS6R131A variant, CerS1 or CerS3 failed to induce Bax activation, the release of cytochrome c or activation of caspase-9.
The resulting inflammatory state is accompanied by maternal leukocyte activation, the release of cytokines from immune cells and uteroplacental tissues, and endothelial cell activation, as well as immune coagulation interactions.
The model also fits to further experimental data available on the qualitative differences concerning tBid formation, caspase-8 activation, the release of some cytochrome c after about 3 hours [ 5] and caspase-9 activity levels which first increase below the value in Figure 3A, but then return to zero.
After HSC activation, the released stimulators activated Ras and promoted the proliferation and differentiation of HSCs through Ras-MEK-ERK pathway [ 33].
Previous studies have demonstrated that activated Bid can mediate Bak activation and the release of AIF and endoG.
Priming of the host cell, through TLR4 and interferon receptors, induces caspase-11 expression, and cytosolic LPS directly stimulates caspase-11 activation, promoting the release of proinflammatory cytokines through pyroptosis and caspase-1 activation.
Neuronal activation triggers the release of neuropeptides and neurotransmitters, thereby further activating mast cells.
We observed that hsFlt3L can generate DCs from peripheral blood precursors; activation stimulates the release of Th1 cytokines and reduces the phagocytic activity of DCs.
