Exact(2)
Faster acquisitions with higher temporal sampling of the BOLD time-course provide several advantages including increased sensitivity in detecting functional activation, the possibility of filtering out physiological noise for improving temporal SNR, and freezing out head motion.
However, although these results show that speech perception and comprehension elicit left inferior frontal and articulatory motor cortex activation, the possibility exists that such activation is consequent to but not critical to perception and comprehension processes (Mahon and Caramazza 2008).
Similar(58)
It was thought most likely that cyclin binds to Cdc2 to form a kinase-active heterodimer (a process called 'stoichiometric' activation), but the possibility that cyclin played a catalytic role in the activation of Cdc2 could not be ruled out.
The involvement of MEK/ERK activation raises the possibility that other upstream signals activating MEK/ERK may increase NFAT activity.
Furthermore, enforced activation of Akt not only blocked PEITC-mediated caspase activation and apoptosis, but also prevented the striking increase in JNK activation, raising the possibility that one of the mechanisms by which Akt protects cells from PEITC lethality is by opposing JNK activation.
Likewise, DESC1 also shares with these two enzymes the capability for pro-uPA activation, revealing the possibility that DESC1 could participate in proteolytic cascades mediated by activated uPA.
In agreement with previously published data [39], we observed that FASN sustains AKT activation, raising the possibility that AKT could function downstream of FASN in promoting cell survival.
Interestingly, individual thalamic neurons are differently tuned to the timing between sensory and cortical activation, raising the possibility that these timing differences are spatially mapped in the thalamus.
In addition, cells in the IBM can have more complex behaviors such as division, death, and activation and the possibility of collision-induced forces when multiple cells are simulated.
The flexibility of scenarios leading to transcriptional activation and the possibility of transcriptional initiation from multiple TFBSs suggest that there may not be a qualitative distinction between a 'functional' and a 'spurious' TFBS.
It should be noted that cells with a MDSC phenotype also upregulated PD-L1 in these studies and exerted a similar inhibitory effect on T-cell activation, raising the possibility of MDSC-mediated T-cell suppression.
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