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First, it was found that I κB α contains a functional nuclear localisation signal that is essential for the efficient post-activation termination of NF- κB signalling by facilitating chromatin release of p50-p65 dimers (Arenzana-Seisdedos et al, 1997).
Both activation and termination of NF- κB activity are strictly modulated at certain steps.
To induce sustained JNK activation, the termination mechanism of the JNK activity is deranged, namely the MKPs are inhibited by reactive oxygen species (ROS).
However, emotion regulation might also result in a paradoxical increase of amygdala activation after termination of voluntary emotion regulation.
Taken together, these findings suggest that Tim coordinates mitotic kinase activation with termination of DNA replication.
During wound closure, the activation and termination of wound healing processes must be tightly regulated to prevent pathological wound responses.
The T-DNA (transferred DNA) construct consisted of complete rRNA coding sequences flanked on both sides by intergenic spacer sequences so as to include any potential elements required for transcriptional activation or termination (Fig. 1A).
In each case, the flight culture samples were compared to culture samples grown under identical conditions on the ground at Kennedy Space Center using coordinated activation and termination times (via real time communications with the Shuttle crew) in an insulated room that maintained the identical temperature and humidity as that on the Shuttle (Orbital Environment Simulator or OES).
RGS proteins serve as scaffolding proteins that coordinate components of GPCR signaling to orchestrate their rapid activation and termination.
Calibration of the Qrr sRNA levels through dosage compensation ensures precise timing of the activation and termination of quorum-sensing-controlled behaviours.
BNST involvement in the activation and termination of the hypothalamo-pituitary-adrenal (HPA) axis response to stress has been well documented in the literature [ 6, 28- 30].
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