Sentence examples for activation signal from inspiring English sources

Following the initial T-cell activation signal, both molecules interact with ligands on APCs to abrogate the resulting immune response.

One proposed model to explain BNip3 function posits that BNip3 can exist as an inactive, latent monomer, which requires a death activation signal to become active.

CD66 is a glycoprotein expressed on neutrophils that mediates the interaction with endothelial surfaces triggering a transient activation signal that regulates the adhesive activity of CD11/CD18 [ 18].

We also refer to these experiments as "low activity" because Leu3, like many transcription factors, requires an activation signal to be fully functional as a transcriptional regulator.

The trans-activation ability of p53 varies with the nature of p53-activating stimuli, the cell type and the duration of the activation signal [ 45, 46].

We clearly show that by inhibiting the activation signal of NLRP3 inflammasome and increasing Nrf2 anti-oxidative activity, Citral effectively prevented the development of ASLN.

In this case, the activation signal that turns the Leu3 DNA binding protein into a transcriptional activator is the binding of a metabolic intermediate, α-isopropylmalate (α-IPM).

NF-κB activation (signal 1), resulting from signaling such as TLRs, induces pro-IL-1β and pro-IL-18 production.

The activation signal is passed through transfer function to produce a single output of the neuron.

Interestingly, our results suggest that in activated DC populations, presentation of phagocytosed particulate Ags is dependent on the nature of the activation signal.

In the present study, we focused on how the activation signal is transferred from the peptide-bound SH2 domain to the kinase domain using segmental labeling NMR methods.