The phrase "activation of telomerase expression" is correct and usable in written English.
It can be used in scientific or medical contexts when discussing the process of initiating or enhancing the expression of the telomerase enzyme.
Example: "The study focused on the activation of telomerase expression to investigate its role in cellular aging."
Alternatives: "induction of telomerase expression" or "stimulation of telomerase expression."
The inefficient activation of telomerase expression in oldest fish might be responsible for this behaviour.
This behaviour might be related to the inefficient activation of telomerase expression in fish older than 3 months.
Comparison of normal and cancer tissue has revealed rearrangement of at least two VNTRs in hTERT and has suggested that minisatellites might be associated with activation of telomerase expression in cancer cells [15].
Comparison of normal and cancer tissue from patients revealed rearrangements of at least two VNTR regions of hTERT, suggesting that the minisatellites might be associated with activation of telomerase expression in cancer cells [ 6].
The DNA from cancer tissues of one patient with a kidney tumor had a simultaneous rearrangement of hTERT-VNTR6-1st and 6-2nd [ 6, 7], an observation that suggests that chromosomal rearrangements involving these VNTRs may be associated with the activation of telomerase expression in cancer.
We observed a significant decrease of telomerase expression with aging (Fig. 6C), confirming our previous results.
Given that BCR-ABL is the specific target of Gleevec, we surmised that Gleevec affects TA by regulating the expression and activation of telomerase via BCR-ABL.
Activation of telomerase activity is thought to be a critical step in cellular immortalisation and transformation.
However, elevated hTERT expression and the activation of telomerase can result in unlimited proliferative ability in tumor cells.
The classic model of activation of telomerase, for which activity has been found in most cancers including cutaneous malignant melanoma (CMM), dictates that enzyme activity is generated by pathological reactivation of telomerase in telomerase-negative somatic cells.
Among the telomerase subunits, hTERT (human telomerase reverse transcriptase) is expressed concomitantly with the activation of telomerase.
