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Within this context, the current data suggest that the theta LFP responses described above reflect an activation of inputs within the MTL [ 4] and/or from afferent activity from other cortical and subcortical networks [ 30] that provides a temporal window for triggering the single neuron firing upon picture recognition a gateway for processing consciously perceived stimuli within the MTL.
When we investigated the expected error with temporally offset inputs, we found that activation of inputs in the preferred direction produced a large difference between the IV plot of combined excitatory and inhibitory activation and the expected arithmetic sum of the individual responses and, correspondingly, in RPC recordings (Fig. 7 B, top).
Thus, although the co-operativity requirement can be overcome experimentally by artificial depolarisation, synchronous activation of inputs is likely to be a major physiological means to achieve this.
Albus [ 20] postulated in his theoretical work that the synchronous activation of inputs from parallel fibre and climbing fibre to Purkinje cell could result in a long-term depression of the parallel fibre synapses and reducing the Purkinje cell output.
Thus we conclude that the EPSPs recorded in CA2 PNs in response to distal stimulation in SLM of CA1 likely results from the activation of inputs from EC LII.
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The vector (a^{(i)}) is activation of input vector (x_{l}^{(i)}) and the (b_j) is learned feature vectors.
After training, the network was able to produce a final correct target semantic pattern, given a particular pattern of activation of input units (letters).
Activations of input nodes are determined exogenously: these are the inputs to computation.
We used manual peripheral activation of PF inputs to PCs but found that this type of input consistently failed to evoke rebounds in the DCN cells.
Based on our simulations, we predict that when the inhibitory input to these cells is blocked (pharmacologically or by selective activation of excitatory inputs) the contribution of NMDA-R currents should become evident from the IV relationship, an effect that has been observed in motoneurons [37], [38].
We conclude that the activation of thalamic inputs has no detectable effects on large-scale spiking activity during cortical UP states.
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