Exact(1)
The next generation of acoustics-based non-destructive evaluation for structural health monitoring applications will depend, among other reasons, on the capability to effectively characterize the transient stress wave effects related to acoustic emission (AE) generated due to activation of failure mechanisms in materials and structures.
Similar(59)
The activation energies of failure modes were calculated.
However, if the carbohydrate determinant has only one site per allergen, such binding between the IgE and allergen would not induce mast cell activation because of failure to crosslink the high-affinity IgE receptor (FcεRI) on the mast cells (6).
It was therefore important to establish whether GC resistance resulted from the failure of Bax/Bak activation, or failure of activated Bax/Bak to induce downstream apoptotic events.
This phenomenon is related to TGFβ-mediated activation of ERK1/2 and failure to activate p38 in response to TLR.
In light of the universal nature of down-regulation of SERCA2a protein/mRNA and its dysfunction in heart failure, whether activation of SIRT1 ameliorates heart failure irrespective of the etiology warrants investigation.
This effect was correlated with loss of PKCδ activation and failure of PKCδ to translocate to the nucleus.
While NIBAN protects β-cells against apoptosis, the activation of CHAC1 indicates failure of the processes restoring β-cell functionality and heralds ER stress-induced apoptosis (Eizirik et al, 2008; Eizirik and Cnop, 2010).
Sperm defects however, are considered the leading cause of activation failure [ 3], and given the role of PLCζ as the oocyte activating factor; it is highly plausible that defective forms, or abnormal function, of PLCζ may be the underlying cause of certain types of male-factor infertility and oocyte activation failure.
These findings show that BDB mutant receptors are defective in kinase activation as a result of failure to recruit Src.
Cells from these tumours show constitutive HIF activation as a result of failure of normoxic recognition, and thus ubiquitylation, by the VHL E3 ligase complex.
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