The phrase "activation of a targeted" is correct and usable in written English.
It can be used in contexts related to technology, marketing, or scientific research where a specific target is being activated or engaged.
Example: "The activation of a targeted marketing campaign resulted in a significant increase in customer engagement."
Alternatives: "initiation of a specific" or "triggering of a focused".
Thus for example if the therapeutic function involves the activation of a targeted laser ray in a small region of a tissue, what was investigated was the compatibility of this function (in terms of precision, guidance, tolerance, thermal impact, biochemical reactions) with the diagnostic function (in terms of bandwidth of the signal, noise, quality of image or sound).
This mechanism would integrate the activity of MLL1 in activation of a target gene, shared target genes, or both [ 81].
A pointed arrow indicates the activation of a target by an activator species, and a blunt arrow represents the inhibition of the target by an inhibitor.
We, therefore, discussed a structural chromatin domain model in which distinct chromatin domains have been "opened" as a result of activation of a target gene.
The structure of the chromatin domain model assumes that opening of the chromatin of an entire cluster depends on activation of a target gene within the cluster.
Our data suggests that the WCC regulates genes involved in plant cell wall degradation indirectly rather than directly, perhaps via activation of a target transcription factor.
We reasoned that targeting the biological process of interest (transcriptional activation of a target gene), rather than a distal symptom of resistance to drug (i.e., persistent viability, elevated proliferation) might identify resistant clones more quickly.
The most thoroughly studied example for the activation of a target protein by the induction of a conformational change is the gating of the P2X7 ion channel by ADP-ribosylation (Seman et al. 2003).
We postulate that Pax3 and Pax7 play a similar role in myogenic cells, such that activation of a transcriptional target or targets is required for progression to differentiation but differentiation is moderately repressed by promoting proliferation.
Intriguingly, our results concerning miR-767 reveal the existence of an unexpected link between DNA methylation and TET genes, whereby genome demethylation can lead to inhibition of TET activities via activation of a TET-targeting miRNA.
Unlike traditional target drug design, which focuses on the inhibition or activation of a single target protein, usually a receptor or enzyme, PPI-based drug design involves inhibition of PPIs interface that mediate many important biological processes by small molecule; it is a novel and creative approach to drug discovery, especially for anti-cancer.
