The phrase "activation of a broader" is correct and usable in written English.
It can be used in contexts where you are discussing the initiation or implementation of a wider or more extensive process, system, or concept.
Example: "The activation of a broader strategy is essential for achieving our long-term goals."
Alternatives: "initiation of a wider" or "implementation of a larger".
In particular, TLT CD4+ T cell activation i) is quantitatively increased, ii) is characterized by the activation of a broader range of T cell clones, iii) is stochastic, i.e. characterized by the absence of shared pattern of TCR perturbation in genetically identical couples of donors and recipients.
Although Scf elicited rapid responses in some intracellular pathways that we interrogated (Ras/MAPK, PI3K/AKT) in all of the HSC/HPC cellular subsets we analyzed, Thpo stimulation profiles were stronger in HSC/MPP (compared to GMP/CMP or MEP) and consisted of the activation of a broader array of intracellular pathways (Ras/MAPK, PI3K/AKT, JAK/STAT).
Because FOXA1 is expressed only weakly in the transformed cells, transduction with a FOXA1 vector might lead to the activation of a broader range of ERα target genes and suppression of the squamous phenotype.
Thus, the concomitant induction of EZH2 and attenuation of Nkx3.1 can explain the activation of a broad dedifferentiation program observed in the transcriptome of ERGhigh and ESE3low tumors.
Those increased levels suggest the activation of a broad range of immune cells during CM as well as their alteration, secondary to the cerebral processes [22], [23].
Recent molecular studies indicate activation of a broad range of defense responses during induced resistance.
Ras-GTPases are potential candidates that can transduce the constitutive and concurrent activation of a broad array of effectors such as ERK and AKT.
The NF-κB family of transcription factors [p65, p50, p52, RelB, and c-Rel] is involved in the activation of a broad range of genes involved in inflammation, differentiation, tumourigenesis, metastasis, embryonic development, and apoptosis [ 11, 12, 14].
The primary effect of O2 generation in the Arabidopsis flu mutant is the activation of a broad range of signaling pathways known to be involved in biotic and abiotic stress responses [ 36, 37].
Remarkably, UPR activation was also observed in regions distant from the primary injury zone, suggesting the activation of a broad ER stress response in the spinal cord after damage.
This is largely related to hypoxia-induced activation of a broad range of adaptive pathways, a process in which the redox-sensitive transcription factor Hif plays a central role [166 169].
