Sentence examples for activation necessary from inspiring English sources

These facts point to three major checkpoints in the process: first the upstream exchange of calcium and potassium, then ceramide domain formation, and finally the downstream scramblase activation necessary for cell lysis.

This result suggests that not only is Src activation necessary for podosome formation, and for the recruitment of Tks5 to podosomes, but that when β-DG is associated with Tks5 in cells, it too is phosphorylated on tyrosine at Y890.

These potent partners are detected in α6+ cells: the pro-survival Bcl-XL was mainly located at mitochondria and the pro-apoptotic Bax translocates to mitochondrial membrane suggesting the conformational activation necessary to apoptosis induction.

Having determined the existence of two post-training windows of mTOR activity that are necessary for IA memory consolidation, we set to identify the extracellular signals that could be driving mTOR biphasic activation necessary for memory processing.

Stress-induced levels of cortisol may promote metabolic activation necessary for sustained physical demands necessary to avoid further injury.

We furthermore show that a small increase of CRISPR transcription rate can substantially decrease the extent of cas gene activation necessary to achieve a desired amount of crRNA.

MAPK plays a major role in diverse cellular and neuronal activities, and its activation is necessary for consolidation of long-term memory and LTP (for review see [32]).

In monolayer culture, autocrine EGFR activation is necessary to activate AKT [ 30], so we determined whether autocrine EGFR activation is necessary for AKT activation in organotypic culture.

As a consequence less activation is necessary to activate the corresponding word.

Similarly, we found that Erk 1/2 activation is necessary for bacterial invasion because it is necessary for the phosphorylation of serine residues in cortactin.

Moreover, chemokines activate resident microglial cells and such activation is necessary for dendritic remodeling to occur [ 18].