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It works as though the activation is tied to the BIOS chip on the motherboard, and this may literally be the case.
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Thus the nuclear repositioning of the MMU3A3 integration locus is tied to activation of EVI1 and clonal immortalization.
The Cohen-Armon group [ 12] previously demonstrated that a signaling pathway involving ERK2 can support sustained DNA-independent activation of PARP-1, which is tied to signal-dependent chromatin modulation and gene regulation.
In our system, the absence of Caveolin-1 led to a significant increase in apoptosis mediated by TGF- β in hepatocytes, which is tied with omitted AKT activation.
CXCL11 expression increased almost 14-fold, and is tied to several chemokines important for extracellular signaling and immune activation in addition to interferon and TLR3 activation.
The race is tied.
Most resource is tied up, 90% plus is already tied up.
(ID10, commissioner) Most resource is tied up, 90% plus is already tied up.
Given that the kinase activity of MEKK1 is required for cell death, JNK is robustly activated by MEKK1, and that prolonged JNK activation has been tied to cell death, it is strongly suggested that JNK activation plays a significant role in MEKK1-dependent apoptosis in response to cytoskeletal disrupting drugs.
ZAK is a MAP3K whose activation has been tied to expression of inflammatory cytokines.
The fate of T cells, activation or anergy, has been tied to both cell cycle progression (Wells et al. 2000) and intracellular calcium flux (Gavin et al. 2002).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com