The phrase "activation is essential for" is correct and usable in written English.
It can be used in contexts where you want to emphasize the importance of activation in relation to a specific process or outcome.
Example: "In order to achieve optimal performance, activation is essential for the enzyme to function properly."
Alternatives: "activation is crucial for" or "activation is necessary for".
COX2 activation is essential for the IS-limiting effects of statins [ 17, 18].
Our results indicate that FGFR4 activation is essential for some of the activities of FGF19, but is dispensable for the beneficial effects of FGF19 on glucose and lipid metabolism, demonstrating the existence of an FGFR4-independent pathway of FGF19 action.
In addition, Erk activation is essential for carcinogenesis, and constitutively activated Erk is found in a variety of human cancers.
However, because the hemodynamic signals reflect underlying neural activity indirectly, characterization of these signals following brain activation is essential for experimental design and data interpretation.
FAK is activated by an initial autophosphorylation at the Tyr 397 residue, and its activation is essential for the regulation of focal adhesion turnover and cell protrusion [ 12, 13].
NF-κB activation is essential for ILK-mediated oncogenic processes, such as anti-apoptotic activity [ 13], survival promotion [ 14], epithelial mesenchymal transition [ 15], cellular extension and resistance to apoptosis [ 16], angiogenesis [ 17], and migration, invasion, and metastasis [ 18- 20].
For instance, Cyclin-Dependent Kinase A (CDKA) activation is essential for cell cycle re-entry during reprogramming9.
Regulation of integrin affinity (activation) is essential for metazoan development and for many pathological processes.
The data suggest that AMPK activation is essential for AICAR-induced survival of Akt-expressing cells when cultured in the absence of glucose.
In summary, our results show that ERK activation is essential for regeneration initiation, but is dispensable for wound healing in planarians (Fig. 3a).
We focus on the stage during the third hour of development, when ERK activation is essential for patterning of the future nerve cord.
