Performance is evaluated primarily in terms of sensitivity (i.e., activation extent, activation magnitude, percent detected trials and effect size estimates) using five different tasks expected to evoke neuronal activity in a distributed set of regions.
Whereas medication appeared to increase activation extent, Figure 2 shows that the spatial extent of activation typically remained lower relative to the control group (see Figures S1 and S2 for activation volumes in the whole brain, and Tables S1 and S2 for details about activation foci).
To gain further insights into the chromatin modifications imposed by gene activation, extent of nucleosome histone acetylation around the map2 promoter region was investigated.
The activation extent of various signal transduction pathways involved in chemo-sensitivity such as the NF-κB pathway, explains how resistant or susceptible a cancer type is towards drugs [ 14].
The apparent disparity between absolute levels of integrin activation and extent of aggregation highlights the large level in integrin reserve believed to exist in platelets.
Little is known about the activation and extent of MAPK signaling in the synovium of patients with psoriatic arthritis.
Addition of cumate to the medium reduced the activation to different extents in the various cell lines, resulting in ON/OFF ratios of 8.6 +/- 2.1, 13 +/- 7.8, 10.3 +/- 6.0 and 7.7 +/- 0.95 in 293, A549, BMAdE1-78, and HeLa cells respectively.
The first of these characteristics, "activation," is the extent to which a person is motivated by his or her work and feels it is meaningful.
This finding mirrors results from a previous fMRI study, which showed that hippocampal activation predicts the extent of reinstatement of a target scene image in parahippocampal cortex, without scene reinstatement in hippocampus itself30.
We show that oxaliplatin acutely activates Src and that combination treatment with dasatinib is synergistic in a cell-line dependent manner, with the level of Src activation correlating with extent of synergy in a panel of six cell lines.
