Phosphorylation of OPN is required for integrin binding and subsequent induction of IL-12 expression in macrophages, and for mediating their activation and spreading [ 23, 35].
We sought to examine the relationship between verbal spreading activation and visuospatial spreading activation by conducting correlations between design frequency and both word frequencies from the COWAT and from the AN test.
Immune responses induced in the initial virus host interaction may have a potentially dual role – containing viral replication or fueling immune activation and viral spread.
We discuss these findings considering the modulatory top down effects of tDCS on subcortical structures via prefrontal activation, and how spreading of activation might be different for healthy volunteers versus depressed patients.
When analyzing such data, previous studies have mainly quantified spatiotemporal patterns [10], [11], [12], global spatial metrics such as area of activation and point-spread function [11], [13], or latency [12], [14], [15].
Much interest has focused on the role of infection in triggering autoimmune disorders, including systemic lupus erythematosus (SLE), by such mechanisms as molecular mimicry, bystander activation and epitope spreading [ 1].
This test is believed to better estimate the non-thrombogenic potential of PEG-grafted surfaces than platelet adhesion tests performed under static condition [ 40], since the contact of platelets with a given surface is a dynamic process that involves adhesion, activation, secretion, and spreading.
Moreover, IPS activation was stronger and spread out over a larger number of voxels for the magnitude comparison task as compared to e.g., listening passively to number words which is also supposed to automatically activate the quantity representation (e.g., [ 2]).
It is thereby logical to expect that an effective peri-surgical anti-inflammatory strategy may affect surgery-induced single cell activation and resulting cancer spread.
This is in accordance with a recent work showing a positive effect of Laminin1 on Erk activation and on cell spreading in hMSC from bone marrow under serum free conditions [31].
