Sentence examples for activation a state from inspiring English sources
Microglia in the aged brain have been shown to be primed for activation, a state of exaggerated inflammatory reactivity and persistent neuroinflammation.
The most commonly accepted explanation for tumour dormancy is the failure of angiogenic switch activation, a state that maintains the balance between proliferation and apoptosis [ 34].
"Then comes a stage of hyper-activation, a state of alertness, where you are always hyper-vigilant of everyone who makes you think of the aggressor," Brillon added.
We therefore believe that a transition from an activation state close to a classical activation state (M1 polarization) to an alternative activation state (M2 polarization) occurred in tsp-1−/− mice [34], [36] [38].
Failure to resolve immunostimulatory signals, as seen during breast cancer, leads to prolonged activation and establishes a state of chronic inflammation.
The analysis above can also be done to find out whether or not the activation level of a state is increasing.
Although this categorization might be an oversimplification, microglia can be polarized into an activation state that is intermediate between a neuro-harmful and a protective state.
In this analysis, if the observed direction of change is mostly consistent with a particular activation state of a biological function ("increased" or "decreased"), then a prediction is made about that activation state.
In bulk peripheral blood mononuclear cells (PBMC), DC may be present in too low numbers or in an activation state unsuitable for inducing a primary T cell response.
Several defects observed in the SLE TCR signaling pathway are suggestive of an activation state and may be due to activation by APC and/or auto-antibodies.
Interestingly, the expression of IL-18 by CD68+ macrophages was observed only within periductal inflammatory foci and in periacinar macrophages adjacent to focal infiltrates, and not in isolated macrophages, an observation that suggests an activation state of macrophages.
