The phrase "activation a series of" is not correct in English.
It seems to be missing a verb or a preposition to make it grammatically complete.
Example: "The activation of a series of tests is necessary for the experiment."
Alternatives: "initiation of a series of" or "triggering a series of".
T cell activation, a series of physiological changes leading to clonal expansion and development of effector functions, commences as T cell receptor (TCR) encounters a cognate peptide in the context of major histocompatibility complex (MHC) presented by specialized immune cells called antigen presenting cells (APCs).
During activation, a series of conformational changes opens up these outer layers to expose the central hairpin, which then spontaneously penetrates the membrane (Parker et al., 1990).
Regardless of the site of the mutation, these mutations result in loss of GTPase activity making this oncoprotein constitutively active and leading to activation of a series of downstream pathways including the RAF-MEK-ERK (MAPK) signaling pathway and AKT-PI3K-MTOR pathway (Fig. 1).
In summary, exercise-induced activity resulted in the transcriptional activation of a series of complex networks of extracellular and intracellular signaling molecules and pathways involved in the regulation of muscle mass, myogenesis and angiogenesis in adult zebrafish, some of which had not previously been associated with exercise-induced contractile activity.
For transcriptional activation activity assays, a series of reporter and effector vectors was constructed.
Although ALK fusion proteins lack the extracellular ligand-binding segment, oligomerization can lead to ALK activation and self-phosphorylation, thereby activating a series of downstream signaling pathways [6].
NFkB1 is present in abundance in cytoplasm of the cell and it is rapidly activated in response to various extracellular stimuli through upstream activation of a series of protein kinases [47], [48].
The abnormal activation of HER2 in case of homodimerization in cancer tissues leads to a cascade of signaling events causing the activation of a series of transcription factors able to regulate many genes generally involved in cell proliferation, survival, differentiation, and invasion [ 26].
Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
The transition from fetal life to air breathing requires the activation of a series of adaptive responses to the sudden transition from the relatively hypoxic intrauterine environment to the relatively hyperoxic extrauterine environment44,45.
In this study, electrochemical methods have been used to investigate the kinetics of activation of a series of typical ATRP initiators (RX) by [CuIL]+ (L = Me6TREN, TPMA or N,N,N′,N′′,N′′-pentamethyldiethylenetriamine, PMDETA) in MeCN.
