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GENERAL MOTORS It's the automotive equivalent of cellphone pocket dialing: in a wide variety of G.M. models, the OnStar telematics system is activating without any input from the driver, whose clue is an unexpected response from an OnStar operator.
Together, these results indicated that SS input achieves control over the fraction of cells activating without affecting the dynamics in the response.
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That is, caspase-9 was activated without support for multiplication and activation by Apaf-1, and the activated caspase-9 may be physically disconnected from the caspase cascade.
For example, a mutation of Val to glutamate in the dimer interface results in a constitutively active procaspase 3. The procaspase is activated without chain cleavage because the mutation shifts the conformational ensemble to an active state.
When moDCs were exposed to the platinum-based chemotherapeutic compound oxaliplatin during activation, significantly higher T-cell proliferation was induced compared to moDCs activated without the addition of oxaliplatin (Fig. 1a and [ 24]).
If the TCA cycle is activated without the respective increase in the volume occupied by mitochondria, this activation probably could have negative consequences for cell survival.
Although an ASK1 mutant lacking the CCC (ASK1ΔCCC) exhibited lower basal kinase activity compared to wild-type, artificially homo-oligomerized ASK1ΔCCC was autophosphorylated and activated without any stimulation.
"The system can be activated without our approval," he wrote.
Additionally, the heating unit can be activated without the spinner in place, presenting a risk of burn to consumers.
Many video games have basic cheats that can be activated, without a Game Shark, by pressing an often thumb-numbing series of buttons on the console's controller.
Whether such alternative pathways would ever be activated without human help, for example in response to environmental changes, is unknown.
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