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Rac and Cdc42 exert their functions by binding and activating to a large collection of their effector molecules.
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MMP-12 is expressed as a 54-kDa inactive proenzyme and is activated to a 45-kDa active enzyme by removal of the propeptide sequence.
Mainly pro-inflammatory at the beginning of infection, blood monocytes can subsequently be reprogrammed from an activated to a suppressive phenotype.
The insula ipsilateral to the site of needling was activated to a greater extent during real acupuncture than during the placebo intervention.
Furthermore, the left superior parietal cortex was activated to a greater extent by MMO than by MBO regardless of the tasks.
Co-cultures on D-PHI showed that monocytes were activated to a wound-healing phenotype (low TNF-α, elevated IL-10), while promoting uPA expression.
However, caspase-3 is not activated to a higher extent as after TNFα plus ActD treatment.
Interestingly, after endocytosis of flu-B cells, GEN3 were found activated to a similar extent (Figure 5A, lower panels).
The mirror neuron system (MNS) has been shown to be activated to a stronger extent if observers view movements that they already have in their repertoire.
In contrast to changes in cell cycle, the apoptosis pathways were activated to a greater degree in mild infection than in severe infection (Fig. 5A).
In response to various stimulations, the response element is activated to a level which correlates with the amount of luciferase, and thus the signal, produced.
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