The phrase "activating target" is correct and usable in written English.
It can be used in contexts related to technology, gaming, or military operations where a specific target is being engaged or initiated.
Example: "The system is now activating target for the next phase of the operation."
Alternatives: "engaging target" or "initiating target".
In the absence of active signaling, Tcfs recruit proteins such as Groucho and Hdac to repress target genes, whereas in the presence of active signaling, β-catenin binds to Tcfs, displacing repressor components and activating target gene expression [ 24].
Western blot analysis revealed that knockdown of Lsd1 increased the total level of H3K9me1/2 in HBV-infected HK-2 cells (Fig. 5a), consistent with an important role for LSD1 in catalyzing demethylation of the repressive epigenetic mark H3K9me1/2 and activating target genes21,22,38.
This flexibility of the central helix may play a critical role in activating target enzymes such as myosin light chain kinase.
Conversely, in concert with the androgen receptor KDM1 targets repressive H3K9 mono- and dimethylation marks thereby activating target genes [41].
Access to the nuclear compartment might be a first step of regulation prior to activating target promoters.
As well as activating target genes essential for self-renewal, the Sox2-Oct4-Nanog complex represses genes initiating differentiation [28].
Similarly, the main regulator of virulence ToxR requires the membrane-anchored co-activator TcpP to activate target gene expression in V. cholerae.
STATs are cytosolic proteins that, upon activation, translocate in to the nucleus to activate target genes.
A simple model postulates that a morphogen activates target genes by directly activating a latent transcriptional activator (Driever et al., 1989).
Finally, we show that dCas9-VPR can activate target genes and cause dominant phenotypes in vivo, providing the first demonstration of dCas9 activation in a multicellular animal.
Early studies suggested that specificity is dictated by sets of differentially induced transcription factors that synergistically activate target genes containing their binding sites.
