The phrase "activating role" is correct and usable in written English.
It can be used to describe a function or position that initiates or stimulates action or engagement in a particular context.
Example: "In the project, she took on an activating role, encouraging team members to contribute their ideas and collaborate effectively."
Alternatives: "catalytic role" or "initiating role".
This is consistent with considerable data showing that myc has a repressive, as well as an activating, role in transcription (for review see [61]).
However, a secondary activating role at later stages of differentiation cannot be excluded.
Recent reports have argued that gene expression is temporally structured in multiple waves in which key transcription factors play a major activating role [ 39].
In the case of Gata2, its reduction mainly caused downregulation of mast cell-specific genes, consistent with the known activating role of GATA2 (Masuda et al, 2007).
The results from the HT29-APC cell line where Apc was activated or β-catenin silenced, imply an activating role of the Wnt pathway on Notch-2 and the downstream target gene Hes-1 [31].
However, and complicating matters further, the cytoskeleton not only plays an inhibitory, but also an activating role during B cell activation, as it is required for microcluster formation and receptor internalization (Brown and Song, 2001; Cheng et al., 2001).
The apparent activating role of Fyn on PPARγ activity through a negative regulation of Erk1/2 is rather intriguing and suggests that other components may modulate Src/Fyn response to ghrelin.
It is of note, however, that MED12 directly interacts with mammalian β-catenin and activates target genes, thus indicating that MED12 also has an alternative activating role [ 48].
The overall supralinearity is in line with an activating role of complexin in exocytosis by a reduction of the activation energy for fusion.
Therefore, we asked whether the putative activating role of 14-3-3 14-3-3 14-3-3tituted by the short couldxy-terminal sequence of a 14-3-3 independent bet otherwisubstitutedus toxin.
