Sentence examples similar to activating rig from inspiring English sources

Based on the results from the expression profiles, we carefully selected 237 gene probes (materials and methods) by activating RIG-I with Agilent DNA microarray.

However, the specific roles of ATP binding and hydrolysis in activating RIG-I for immune signaling have not been defined or differentiated.

Even in this case, the requirement for CTD end-capping and the extremely weak affinity for internal duplex sites underscore the importance of an available duplex terminus for activating RIG-I signaling.

We note from co-immunoprecipitation experiments, that IKKγΔ associates with MAVS in the absence of ssRNA infection (Figure 8A), suggesting to us, that IKKγ-MAVS complex may be a stable, pre-formed complex whose activity is initiated by binding activated RIG-I.

ERV transcripts then activate RIG-I and cGAS in the cytoplasm.

Strikingly, endogenous retroelements, including ERVs and short interspersed elements (SINEs), can activate RIG-I.

Similar therapies have also been found in pancreatic cancer, where the synthetic siRNA used for silencing the TGF-β gene can simultaneously activate RIG-I and result in enhanced antitumor efficacy against pancreatic cancer (Ellermeier et al., 2013).

Influenza viral RNA is known to activate RIG-I and PKR [84].

Using DEAE-dextran, polyI C is incorporated into the cytoplasm to activate RIG-I/MDA5.

Thus, the inability of viral RNAs to activate RIG-I-dependent IFN induction correlates with the presence of a 5' monophosphate.

EBV encoded small RNAs are transcribed by RNA polymerase III and are known to activate RIG-I [38].