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Among the genes widely characterized for disease resistance, the rice WRKY45 gene has been found to play a crucial role in resistance to bacterial and fungal blast induced by benzothiadiazole (BTH), a so-called plant activator that protects plants from diseases by activating plant innate immune system (Shimono et al. 2007).
Whereas this harpin was expressed without a signal peptide, the authors ascribed the necrotic phenotype to leakage of intracellularly accumulated HrpZPss from the E. cichoracearum-penetrated plant cells, allowing the protein to access the plant cell exterior where it normally acts, thus activating plant defense mechanisms.
Indeed, the product of β-glucanase might operate as an elicitor activating plant metabolism.
Jasmonic acid (JA) and salicylic acid (SA) play an important role in activating plant defensive responses against insect pests.
Plants can differentially perceive various kinds of insect attacks and respond appropriately through activating plant defenses including regulation of PIs at transcriptional and post-translational levels.
As was the case for genes from the AP2 family, which have been identified previously in the gene network activating plant freezing tolerance in Arabidopsis[ 61] and Triticum aestivum[ 62].
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It was found, at early stages (7 and 45 days old) in greenhouse, that H. seropedicae in mixture with HS from vermicompost activated plant metabolic processes such as enhancement of plasma membrane H+-ATPase activity, alteration of both sugar and N metabolism and increase of net photosynthesis.
They form partly dsRNA structures and activate plant's RNA silencing machinery, but can resist this suppression by producing active RSSs [ 21- 23].
These receptors initiate signaling processes that activate plant defenses.
A second group of genes like avirulence genes are known to activate plant defense responses.
Thus, the genes that activate plant defense responses are unlikely to be a good strategy to increase disease resistance.
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