Sentence examples for activating initiation from inspiring English sources

Subsequently, mTOR phosphorylates and activates the 70-kDa ribosomal protein S6 kinase (p70S6K), which results in increased translation either directly or indirectly by activating initiation and elongation factors, eIF-2, eIF-4E (through 4E-BP) and eEF-2 (Bodine et al. 2001b; Hornberger et al. 2001) (Suppl. Fig. 2C).

The structural and biochemical studies of Tth CarD/RPo complexes presented here reveal how the widely distributed transcription factor CarD interacts with RPo to activate initiation.

These downstream effectors activate protein synthesis by activating translation initiation and elonga tion factors, including eIF4E, eIF4B, S6, and eEF2 [ 32, 38].

The downstream protein of TRAF2/3 can activate consecutive initiation of MEK4 and MEK7, resulting in the activation of stress-activated protein kinases JNK1/2 [ 29].

In terms of functions, initial data suggested that the small mediator functions to activate transcription initiation in vitro, while the large mediator is inactive or acts as a transcription repressor (Taatjes et al. 2002).

As indicated in the bottom panel of Figure 1(c), prostratin treatment increased the products corresponding to initiation as well as elongation to a similar extent, suggesting that prostratin was able to activate transcription initiation with no apparent effect on transcription elongation.

There have been new insights into the molecular mechanisms that regulatory proteins use to sense a given signal and to activate transcription initiation from the cognate promoters.

CCS52A1 encodes an endoreduplication factor, in which mutation could activate trichome initiation [ 13].

GaHOX1 and GaHOX3 with high sequence similarities to GL2 could also activate trichome initiation when expressed in Arabidopsis [ 19].

Exposure of DiFi cells to mAb 225 activated the initiation caspase-8, which was detectable between 8 and 16 h after exposure of the cells to the antibody.

One of the three signalling transducers activated during initiation of the UPR, the inositol-requiring protein-1 (Ire1) pathway, has dual actions.