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Genes including Heat shock protein (Hsp) 70kD (Hspa5, Hspand and Hsp 90kD (Hspca) interact with Stat3 by binding to each other and positively activating each other; caveolin can assist in the binding procedure.
This concept agrees well with the theoretical prediction of Beltrami and Jesty that a biochemical system composed of two enzymes reciprocally activating each other in the presence of flow, one enzyme being membrane-bound and another being soluble, will depend on the wall shear rate in a threshold manner[ 17].
The current accepted model of adipogenesis starts with the increased expression of C/EBPβ, which then induces the expression of PPAR-γ and C/EBPα forming a positive feed-back loop by activating each other's expression.
C/EBPβ then induces expression of PPARγ and C/EBPα, which form a positive feedback loop by activating each other's expression and play roles at a later stage by inducing and maintaining the expression of adipocyte-specific genes (Rosen and MacDougald 2006; Tontonoz and Spiegelman 2008).
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We explore a gene network motif in our experimental synthetic biology studies of two genes that mutually repress and activate each other with self-activation and self-repression.
Belongs to the MAP (mitogen-activated protein) kinases that sequentially activate each other.
Caspases further activate each other through cleavage next to aspartate residues, amplifying caspase activity down a cascade, accounting for many of the morphological changes associated with apoptosis.
Fig. 26 Implementation of dense crossbar of PCM and selector devices for non-Von Neumann computing where neuron activates each other through dense networks of programmable synaptic weights.
As will be seen in the examples presented below, it is typical for a number of these types of invocatory mechanisms to reinforce or help activate each other in any segment of text to provoke readings of attitudes.
This study investigates the use of a ground slag, and a high-lime fly ash, rich in free lime and sulfates, to activate each other and render mortars which don't incorporate any Portland cement or an added chemical activator, but still have useful strengths.
It was recently reported that Sirt1 and AMPK could activate each other [37], [38], [39].
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