Sentence examples for activating cell from inspiring English sources

Thus, mainly T cells stimulated by DCs are able to express surface CD152, showing that the activation history and activating cell type (DC versus B cell) regulate CD152 expression on T cells.

It is a typical situation described by Lichtenthaler (1988) as eu-stress, a mild stress activating cell metabolism and increasing physiological activity vs. dis stress, having a negative, damaging effect.

mTORC1 is known to activate protein synthesis and cell growth through regulating pS6K and 4E-BP1 activity, whereas mTORC2 phosphorylates Akt on Ser-473, activating cell growth, proliferation, and survival [ 43, 44].

Notably, miR-210 facilitates tumor proliferation by activating cell cycle checkpoint and inhibits tumor cell death by decreasing the activity of caspase-8 or lowering the level of reactive oxygen species encouraging tumor cell immortality [ 93 95].

Therefore, owing to the higher membrane permeability of the mitochondria, cytochrome C was rapidly released into the cytoplasm, activating cell death-signaling proteins (caspases) and promoting the cascade reaction of cellular apoptosis.

In response to radiation, cells activate cell cycle checkpoints in G1, S and G2 phases in order to repair genomic defects, maintaining its integrity, or prevent cell division by activating cell death mechanisms (Kastan and Bartek 2004).

HMGB-1 released into the circulation in sepsis syndromes is considered a key signalling molecule in the inflammatory hub concept of severe sepsis, activating cell-to-cell signalling, procoagulant activity and late phase responses [ 7].

Cells respond to DNA damaging agents by activating cell-cycle checkpoints.

Some experimental studies suggest that induced hypothermia may have a beneficial effect by reducing energy requirement and activating cell-protecting pathways [ 17].

ATM, ATR and DNA-PKcs are not only required for activating cell-cycle checkpoints but they also phosphorylate many substrates involved in other aspects of the DDR.

Therefore, telomeres in yeast must be at least 16 times less potent than DSB-induced ends in activating cell-cycle arrest.