Sentence examples for activating a cascade of from inspiring English sources

Experts theorize that limited access to energy alarms the body, so to speak, activating a cascade of biochemical signals that tell each cell to direct energy away from reproductive functions, toward repair and maintenance.

TLR4 is a member of the TLR family of pattern recognition receptors that generate innate immune responses to pathogens by activating a cascade of pro-inflammatory events [ 5].

Thermal stress trigger cellular and organismal responses activating a cascade of events that may lead to pathological conditions and ultimately to death.

A typical feature of GPCR signaling is that by activating a cascade of signal transduction mediators the signals can be amplified.

In CAIA it is possible to study the inflammatory phase of the immune response without involving the primary phase by activating a cascade of reactions involving complement [ 22] and Fcγ receptors [ 23].

Inhibition of TOR1C initiates autophagy by activating a cascade of phosphorylation events, which leads to the formation of a cup shaped membrane – termed the "isolation membrane" – in the vicinity of the targets termed the "phagosome assembly site" (PAS) (Fig. 1).

During brain development, proper synaptic activity must activate a cascade of genes involved in transforming immature neuronal connections into functional circuits.

A wide variety of extracellular stimuli can activate Kras, and the activated form, in turn, activates a cascade of signals that ultimately regulate cell growth, differentiation (McCormick, 1989) and apoptosis.

Subsequently, the activated IRS-1 can activate a cascade of phosphorylation-dephosphorylation reactions, including 85-kDa of phosphatidylinositol-3-kinase (PI3K-p85) and serine/threonine kinases Akt/PKB (e.g. Ser-473 and Thr-308 for the Akt/PKB isoform), leading to glucose transporter 4 (GLUtranslocationtion and intracellular glucose metabolism [ 4].

Once a stroke occurs, permeability of the blood-brain barrier (BBB) promptly increases and activates a cascade of inflammatory responses which includes glial activation, neutrophil infiltration, increased expression of selectins and other intercellular adhesion molecules on BBB endothelial cells, as well as an infiltration of immune cells, leading to ischemic brain injury [ 37– 37].

Orthodontic forces cause micro-trauma to the periodontal ligament and activate a cascade of cellular events associated with local periodontal inflammation [7].