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Whether the activation of response(s) in Xen-R could be attributed to a change in a key gene that activates pathway(s) involved in the response, or the independent activation of different response processes would need to be elucidated.
Here, tumor cells secrete Hh ligand that activates pathway signaling in neighboring stromal cells that in turn, are thought to elaborate factors promoting tumor cell growth and survival.
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This suggests that castration itself activates pathways that lead to prostate cancer recurrence and metastases [ 4].
12- O-tetradecanoylphorbol-13-acetate likely activates pathways of signal transduction regulating cell proliferation and differentiation.
These data indicate that hyperglycemia activates pathways involved in muscle atrophy.
A non-radiative de-activate pathway is assigned to the non-planar conformation at excited state.
In Jurkat cells, NO inhibits the NF-kappaB activating pathway in the cytoplasm at a step proximal to the degradation of IkappaBalpha.
The three Hh ligands (Sonic, Indian and Desert) activate pathway signaling by binding to the cell surface receptor Patched (PTCH).
This is understood by noting that only the activating pathway is conveying spatial information.
We determined the relevance of the VEGFR-1 activating pathway for colon cancer (CC) metastasis.
Figure 5 summarizes these complex mechanisms of the VEGFR-1 activating pathway in CC tissue.
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