Several studies used measures that assessed daytime disruption due to coughing (e.g., cannot perform most usual activates due to coughing) [ 8, 10, 12- 15].
3 For example, the anti-wrinkle activity of formulated fruit extract may be due to the suppressive effect of some phytochemicals on C-Jun N-terminal kinase or MMPs (MMP-1, MMP-3, and MMP-9) which activates due to oxidative stress.
One dilemma, however, resides in the issue if a gene is demethylated due to activation or activated due to demethylation.
Whilst nicotine at lower doses (0.1 1 mM) activated FOXM1, nicotine at 10 mM did not activate FOXM1 activity due to toxicity (Fig. 4A).
Finally, brain stress systems are activated due to noradrenergic activation of corticotrophin releasing factor from the hypothalamus and the amygdala [ 21] In concordance with this an elevation of cortisol secretion takes place during early opioid abstinence [ 22].
It is not clear whether the diminished activation of these signalling molecules reflects a reduced need for them to be activated due to the presence of activated Akt or a negative feedback loop by which activated Akt can suppress activation of ErbB3-dependent signalling.
In JW1176 (Δ fadR) and LMB015 (Δ fadR Δ marR), the biosynthesis of unsaturated fatty acid could not be activated due to deficiency of the activator FadR, thereby elevating the content of the saturated fatty acid, palmitic acid.> -wrap-foot> The amounts of fatty acids were given as the ratio (in percent) to the total intracellular fatty acid.
The mitochondrial apoptotic pathway is activated due to cleavage of Bid by activated caspase-8 and by the production of reactive oxygen species (ROS).
In the case where OMI activity was absent or unable to be activated (due to PINK1 deficiencies) during conditions of less demand (but when substrates were plentiful), there would be little or no protease capable of controlling IDH3A and PDHB import.
NF- κB pathway can be activated due to TNF α secreted by activated macrophages, fibroblasts, Kupffer cells and a variety of tumor cells including breast carcinoma, colon carcinoma and B-cell lymphoma.
The results are shown in Table 2. Different pathways are activated due to FGFR1 upregulation such as, for example, mitogen-activated protein kinase (MAPK) signalling (Weiss et al, 2010) a key pathway in carcinogenesis and maintenance of lung cancer (Neuzillet et al, 2014).
