Sentence examples for activates a large number from inspiring English sources

By contrast, activated CREB initiates transcriptional remodelling that activates a large number of adipose-related genes; in this process, PPARγ plays a major role in complex transcriptional cascades.

This gene directs the expression of a mutant, constitutively active tyrosine kinase called Bcr-Abl that activates a large number of proteins controlling cell cycle and inhibiting DNA repair, resulting in speeding up of cell division and incorporation of further genetic abnormalities [16].

Jak-STAT signaling activates a large number of antiviral genes that are normally quiescent or present at low levels.

We showed for the first time that PS deprivation activates a large number of GABAergic neurons only in the vlPAG/dDpMe region.

Flavonoids also exert their chemopreventative effect via inhibition of certain phase I metabolizing enzymes, such as cytochrome P450 which metabolically activates a large number of procarcinogens triggering carcinogenesis.

The degradation of JAZ proteins relieves the JAZ-mediated repression of the JA signalling pathway and thereby activates a large number of JA responsive genes [ 57, 58].

The MTS 3- 4,5-dimethylthiazole-2-yl -5- 3-carboxymethoxyphenyl -2- 4-sulfophenyl -2H-tetrazoliu MTS 3- 4,5-dimethylthiazole-2-yl -5- 3-carboxymethoxyphenyl -2- 4-sulfophenyl -2H-tetrazoliua large nuMTS 3- 4,5-dimethylthiazole-2-yl -5- 3-carboxymethoxyphenyl -2- 4-sulfophenyl -2H-tetrazoliu

In their active, GTP-bound conformations, the four RAS proteins engage and activate a large number of downstream signaling pathways to varying degrees.

Ang II acts as a mitogen in vascular smooth muscle cells by activating several signaling pathways, such as that of phospholipase C, phospholipase A2, and phospholipase D, as well as activating a large number of kinases, such as tyrosine kinases, mitogen-activated protein kinases (MAPKs), c-src kinase, Janus-associated tyrosine kinase, and receptors with tyrosine-kinase activity.

This is triggered by superantigens, which are powerful toxins produced by the bacteria and which activate a large number of the human immune system's T-cells in the bloodstream.

It activated a large number of regimental and brigade commands to fulfill various training roles.