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Stat5 is strongly activated towards the end of pregnancy, persists in an activated state during pregnancy and is rapidly inactivated after cessation of suckling.
It has been hypothesized that cognitive and memory-related brain function in transsexuals during cross-sex hormonal treatment might be activated towards that of the subjective gender.
The amino-acid promoters were mostly activated towards the end of the exp.
The aromatic core of phenylazocarboxylic esters is highly activated towards nucleophilic aromatic F-substitution (cf. Figure 8) [ 102].
Specific members of this protein family are activated towards oncogenes by chromosomal translocations [ 17] placing a structural ETS transcription factor gene under the control of an androgen-responsive promoter, resulting in its deregulation and overexpression.
Unlike stable plaques characterized by a chronic infiltrate of macrophages, vulnerable plaques display an inflammatory infiltrate composed by T cells activated towards a Th1 pathway, and whose recruitment is regulated by chemokines, cytokines, and their receptors [ 1, 2].
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Hsp90 has preferential activity towards activated BRAF as compared to normal BRAF [16].
As a result, the sorption effectiveness of thermally activated zeolite towards trace element ions was not further diminished in aqueous solutions.
Palmitate (0.2 mM) alone did not induce insulin resistance in muscle cells, yet conditioned media from palmitate-challenged muscle cells selectively activated macrophages towards a pro-inflammatory phenotype.
Macrophages are rapidly activated and polarized towards a M1 inflammatory phenotype ("classically activated" macrophages).
However, modulation of microglia activation towards an alternatively activated phenotype, favoring neuroprotection, can modify the outcome of some experimental models of neurological diseases [ 17].
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