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If the spectrum of immunity is enlarged, differentiating low reactive concinnous immune reactions from fully activated responses against the 'other' is only a matter of degree.
The mechanochromic response of this material was observed during an investigation into light activated responses in shape-memory polymers (SMP).
(G – I ) Comparison of activated responses of Ctrl and KO mice during day 1 (G ), day 2 (H ), and day 3 of conditioning (I ).
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In the absence of any scaffold protein, no activated response regulator activity is observed (Supplementary Figure S2, Supporting Information).
Lower levels of inhibition seem to affect the duration of the activated response, and increasing inhibition levels eventually delay the response and limit the activation maxima.
ROS and RNS are key components of the antimicrobial arsenal of the innate and the activated response of macrophages against a variety of intracellular pathogens [25].
Inhibition of GSK3β with the specific inhibitor TDZD-8 decreased SFN-activated NQO1-ARE transcriptional response, confirming the role of GSK3β in the SFN activated response (Fig. 6A).
When ET-1 was applied following ACh, the ET-1 activated response was greatly attenuated, demonstrating that ACh could desensitize the response to ET-1.
Similar to the wound-healing process, an activated response of the tumour stroma may initially be triggered in an attempt to restore tissue homeostasis.
The activated response was measured in the same oocyte at 3 5 minutes after addition of 4 mM sodium nitroprusside (SNP), which elevates endogenous cGMP levels.
To confirm that the green-light sensing system induced the lysis genes, we investigated the mRNA level of T4 holin, whose transcription was designed to be regulated by the green-light activated response regulator CcaR.
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