Sentence examples for activated platelet adhesion from inspiring English sources
In vitro, GMP-140 mediates activated platelet adhesion to neutrophils (PMN) and monocytes, causing the formation of leukocyte-platelet conjugates.
Inhibition studies suggest that activated platelet adhesion to ECs is mediated by P-selectin and GPIIb-IIIA, and tumour cell adhesion to EC-bound platelets--mainly by GPIIb-IIIa.
Thrombosis is a major cause of morbidity and mortality and is closely related to activated platelet adhesion, aggregation, secretion functions, and activation of intrinsic and extrinsic coagulation systems, which cause blood coagulation and fibrin formation [ 3].
Results show that neutralized acid-soluble type I collagen films do not enhance blood coagulation, do not alter normal viscoelastic properties of blood and slightly activate platelet adhesion and aggregation.
In mice, CD62P+ activated platelets mediate adhesion of lymphocytes to endothelium leading to recruitment of T cells to the place of injury [ 28].
Spontaneous and ADP-activated platelet adhesion were investigated using a colorimetric method.
Spontaneous and ADP-activated platelet adhesion to human fibrinogen (2 mg/mL) coated in multi-well microplates was investigated using a microplate reader (Elx 800; Bio-Tek Instruments Inc., Winosski, Vermont, USA) at 405 nm as described previously [ 9].
Even low concentrations of the extract (1 μg/mL) contributed to a 22 % reduction in the ADP-activated platelet adhesion to fibrinogen-coated surfaces (from 14.22 ± 1.5 to 11.08 ± 1.2%% of platelets introduced into the well).
The activity of thrombin and plasmin was determined by means of chromogenic substrate S-22388, S-2251) The aronia extract contributed to the reduction in spontaneous and ADP-activated platelet adhesion.
We have developed a range of novel ligand-conjugated MPIO for molecular MRI of endothelial adhesion molecules, such as vascular cell adhesion molecule-1 (VCAM-1) and P-selectin expressed in vascular inflammation, as well as activated platelet thrombosis.
Thrombin exerts a variety of cellular effects, such as activating platelet-tumor adhesion, tumor growth, metastasis, apoptosis, and tumor-associated angiogenesis [ 2– 4].
