Sentence examples for activated pathways in from inspiring English sources

Alternatively, elevated circulating lyso-PCs may not be functionally active in this process but represent activated pathways in the synthesis or metabolism of phospholipids and phosphatidylcholine and, thus, in the generation of hepatic endoplasmic reticulum stress (40) (Supplementary Fig. 2).

For several aberrantly activated pathways in hepatocarcinoma, surrogate markers of activation can be assessed by immunohistochemistry, although associations with in vivo response to targeted therapies are still lacking.

The PI3-kinase pathway is one of the most commonly activated pathways in cancer and the focus of intense effort to capitalize on its therapeutic potential.

Targeting differentially activated pathways in TPCs may provide new therapeutic strategies for treating sarcoma.

The AKT/PKB kinase is a key signaling component of one of the most frequently activated pathways in cancer and is a major target of cancer drug development.

We identified 29 differently activated pathways in RPE-choroid AMD phenotypes.

3 4 In a systematic study of molecular signatures in GC, mitogen-activated protein kinase (MAPK) was found as the most frequently activated pathway in this deadly disease.

Human data suggest that STAT5 activating pathways in mast cells are operational in a subset of AD patients.

It is likely that, apart from the phosphorylational regulation, Ras could also activate "pathways in cancer" at the transcriptional level.

These genes encode proteins that activate pathways in the endosperm that promote the formation of cell walls, which is a crucial stage in seed development.

In this context, the present study focusses on the expression profiles of members of the VEGF receptor-1 (VEGFR-1) activating pathway in colon cancer (CC) tissue.