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Interestingly, PPARα is an important activator of fatty acid catabolism and may be activated not only by AMPK, but also by fatty acids, fibrates, and eicosanoids [ 48].
AKT can be activated not only by extracellular growth factor signals, but by activation of DNA-PK (DNA dependent protein kinase) which was described to be overexpressed in platinum resistant high-grade serous ovarian carcinomas [ 38].
They sell it as a natural, non-invasive therapy, using non-toxic light-sensitive substances such as chlorophyll which "explode" with oxygen, killing the cancer cells when activated not only by light but also by ultrasound waves which, they say, can reach every part of the body.
Moreover, the insular cortex is activated not only by taste but also by non-taste information from oral stimuli.
The MOP receptor is activated not only by morphine, but also by other opiate drugs such as methadone and endogenous opioids such as endorphins.
At Parma, Keysers helped identify mirror neurons that were activated not only when the monkeys observed an action but also when they heard a sound associated with it.
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Vorinostat might activate not only the virus, but also genes that are supposed to remain silenced, causing side effects.
Researchers using functional brain imagery have confirmed that in such situations the blind person activates not only the parts of the cortex devoted to touch, but parts of the visual cortex as well.
She draws on recent research with functional magnetic resonance imaging (fMRI), a technique that maps blood flow in the brain during a given task, to show that meaningful squiggles activate not only the occipital regions responsible for vision but also temporal and parietal regions associated with language and computation.
HMGB1 for example can activate not only RAGE but also TLR4 [38].
A longer water residence time in the clays is the second factor, which activates not only solubility and dissolution of F−-bearing minerals, but also anion exchange between F− and OH−.
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