The phrase "activated mostly by" is correct and usable in written English.
It can be used to describe the primary triggers or causes that initiate a particular action or response.
Example: "The device is activated mostly by motion sensors, ensuring it responds to any movement in the vicinity."
Alternatives: "primarily triggered by" or "mainly initiated by".
While some substrates are functionally inactivated upon caspase-mediated cleavage, other proteins and enzymes can be activated, mostly by removing an inhibitory or regulatory domain within the caspase target.
Accordingly, we were able to demonstrate that the effect of DIM treatment on CYP1A1 and GREB1 expression is mediated by ERα, which, in this case, is activated mostly by the PKA signaling pathway.
The canonical NF- κB pathway is activated mostly by the stimulation of proinflammatory receptors, such as the TNF receptor superfamily, the Toll-like receptor family (TLRs), and cytokine receptors for the interleukins [ 88].
Rop GTPases are activated mostly by a type of GEF proteins absent in Opisthokonts – the PRONE-GEFs [ 105] - whose activity is regulated by interactions with specific transmembrane Ser/Thr receptor kinases (RLKs; [ 105, 106]).
In cells, MDA5 is activated mostly, if not only, by >2 kb long viral dsRNA [ 6, 39], higher-order viral RNA structures [ 40] or >0.5 kb of the synthetic dsRNA mimic poly(I C) [ 6].
The anterior cluster is mostly activated by cognition, whereas the posterior is mostly activated by interoception, perception and emotion.
Both inactivation by Na [which does not involve an interaction with the CBDs (25, 26)] and activation via occupation of CBDs are strongly modulated by binding of the phospholipid PIP2 to cationic sites of the cytoplasmic loop, dubbed the exchanger inhibitory peptide (XIP) domain: PIP2 activates NCX mostly by antagonizing Na-dependent inactivation (27, 28).
It is mostly activated by cysteine while hydrogen sulfide and sodium cyanide are less effective (Bencucci et al. 2011).
From another viewpoint, a counseling therapist may see depression not as a biochemical illness or disorder but as "a species-wide evolved suite of emotional programs that are mostly activated by a perception, almost always over-negative, of a major decline in personal usefulness, that can sometimes be linked to guilt, shame or perceived rejection".
Furthermore, because its expression is mostly activated by transient signals, the role of CEBPD in vivo may be modulatory and only uncovered when cells are investigated in response to specific stimuli.
While SODs are responsible for the constitutive removal of reactive intermediates generated from normal metabolic processes, NRF2 is mostly activated by signaling mechanisms that change the cellular thiol/disulfide redox status [9].
