Sentence examples for activated members of from inspiring English sources

These are notable because of their production from IL4- or IL13- alternatively actIL13- alternativelythe mononucleactivatedyte systemembersh includes mofocythe, mononuclear, and dendritic cells [22], [23].

An accurate molecular predictive model of TKI response should include activated members of the EGFR pathway.

We have previously shown that Fhit directly interacts with activated members of the Gαq family (Gαq, Gα14, and Gα16) via their α2-β4 region without affecting Gαq-induced PLCβ activation [ 15].

To ascertain that Fhit can truly interact with activated members of Gαq, we examined the association between Gα16QL and Fhit by reciprocal co-immunoprecipitation using an anti-Gα16 antiserum to pull down Fhit from lysates of HEK293 cells expressing wild-type Gα16 or Gα16QL; Fhit was indeed co-immunoprecipitated along with Gα16QL, but not with wild-type Gα16.

Although a wide range of cell signals of either extracellular or intracellular origin can lead to the activation of various pathways eventually resulting in the initiation of apoptosis, the major cause of the cell death is related to the organized degradation of cellular organelles by activated members of the caspase family of cysteine proteases.

LMP1 functions as a constitutively activated member of the tumor necrosis factor receptor (TNFR) superfamily, activating a number of signaling pathways (NF-κB, ERK-MAPK, JNK/AP1, PI3K) in a ligand-independent manner [34].

The latent membrane protein-1 (LMP1) is expressed by Epstein Barr virus during viral latency and displaying properties of a constitutively activated member of the TNF receptor family.

The activation of this pathway is most notable in cancers that have either inactivating mutations of the PTEN gene (e.g. glioblastoma, melanoma, prostate cancer and endometrial carcinomas) or overexpression of an activated member of the epidermal growth factor (EGF) receptor family (e.g. Her2/neu in breast cancer) (Luo et al, 2005).

The prototypical Ca2+-activated and pH-activated members of this channel family are Slo1 and Slo3, respectively.

Arachidonic acid directly activates members of the mitogen-activated protein kinase superfamily in rabbit proximal tubule cells.

Consequently, p185-erbB2 is assumed to be activated by hetero-dimerization with another ligand-activated member of the EGFR family [ 6].