Sentence examples for activated lead from inspiring English sources

Platelets do, however, express high levels of functional receptors for IGF-I that, when activated, lead to the tyrosine phosphorylation of insulin receptor substrate (IRS -1 and IRS -1and their association with the p85 subunit of PI3-K (8).

Both esculetin and CAPE inhibited NF-κB activation, and esculetin also inhibited 5-LOX, representing two pathways that when activated lead to inflammation [66,67].

DLGR2, once activated leads to the activation of the cAMP/PKA signaling pathway [ 11- 13].

We show that IL-1β signaling is present in myocytes and when activated leads to myocyte atrophy in vitro.

In the radiation hydrodynamics simulations of Hosokawa et al. (2012b) and Hirano et al. (2014), the lower accretion rates in halos in which HD cooling was activated led to final stellar masses ({gtrsim}10mbox { M}_{odot}).

We have previously shown that there is sufficient pro-collagenase early in the cartilage culture which, if activated, leads to cartilage collagen resorption [ 21].

Cholangiocytes are the sole cell type in the liver that express secretin receptor (SR) which, when activated, leads to an opening of the chloride bicarbonate (Cl−/HCO3−) exchanger.

AS160 is fully activated by partial activation of Akt, at an Insulin concentration of around 1 nM, but even when fully activated leads to only a partial translocation of GLUT4.

The pro-apoptotic protein p53 plays a major role in cellular response to DNA damage, and when activated leads to cell cycle arrest and DNA repair or to apoptosis [ 26, 53, 54].

These genes represented a panel of putative cellular biomarkers which were induced by lead and whose expressions remained activated after lead was removed from the medium.

Upon increased respiration during exercise, mechanoreceptors in the upper airway mucosa are activated and lead to a higher activity of the muscles of the upper airways [ 29].