Sentence examples for activated in the context of from inspiring English sources

Both PTP and c-Src can be activated in the context of H/R, and the activation of c-Src in this context may therefore involve either direct oxidative activation or indirect activation as a consequence of PTP oxidation; this has not been tested yet.

We are interested in studying novel endothelial and vascular smooth muscle cell signaling pathways that are either disrupted or activated in the context of pulmonary arterial hypertension (PAH), a rare disease with high mortality (up to 45% at three years after diagnosis).

In the case of excessive activation of this inhibitory network in the prefrontal cortex and in other interconnected neural structures activated in the context of persistent pain, the system might become dysregulated and even disrupted.

However, current understanding of how these pathways are activated in the context of developmental programming remains poorly defined.

This paper discusses the concept of the agINFRA project and presents its major outcomes, as adopted by existing initiatives activated in the context of agricultural research and education.

In the case a RCT will be activated in the context of the study, drugs compared in the RCT part of the study will be furnished by the Sponsor(s).

Finally, miR-21 is upregulated under conditions in which EGFR signalling is activated, especially in the context of EGFR-activating mutations, and is suggested to be related to lung carcinogenesis in never smokers (Seike et al, 2009).

Overexpression of ARP-1 or Ear-3/COUP-TF with CETP promoter/chloramphenicol acetyltransferase gene reporter plasmids repressed transcriptional activity of the CETP promoter containing sequences up to -300, but activated transcription in the context of larger constructs containing sequences up to -636.

The genomic positions and temporal programs of metazoan replication origins have been determined within various cell types by genome-wide sequencing analysis (Gilbert 2010), but the mechanisms that regulate recruitment of replication initiation factors to origins of replication and how origins of replication are activated, especially in the context of development, remain poorly understood.

In particular, reversion of either T268A or F87V in P-I263F markedly reduces aziridination productivity (Table S2) and demonstrates some nonadditivity among the activating mutations (i.e., I263F is activating only in the context of T268A).

In our AI-resistant breast cancer model we have shown that PSAP is capable of upregulating and activating AR in the context of high HOXC11 expression.