The phrase "activated in large" is not correct and lacks clarity in written English.
It may be intended to describe something that is activated on a large scale or in a large quantity, but it needs additional context to be meaningful.
Example: "The new software features were activated in large quantities to meet the demand."
Alternatives: "activated on a large scale" or "activated in significant amounts".
Their brains, unlike those of the sedentary animals, showed evidence that the shushing neurons also had been activated in large numbers, releasing GABA, calming the excitable neurons' activity and presumably keeping unnecessary anxiety at bay.
As well as releasing the iPhone 5S and 5C, Apple also refreshed its iPad line with the iPad Air and iPad mini, and if those - which have iOS 7 installed already - have been bought and activated in large enough numbers they could raise the numbers of iOS 7 devices recorded by Chitika and Mixpanel.
The immunoregulatory receptor genes, IL4R IL6R and IL20RA and the thrombin and thrombin-like receptors F2R and F2RL1were also identified among the list of genes activated in large follicles (Table 1).
The PI3K/mTOR pathway is activated in large number of cancers which provides a rationale for the combination of a p53 modulating drug and an mTOR inhibitor [ 78, 106, 107].
The IL-6 signalling pathway (Additional file 5: Figure S4), associated with inflammation and acute phase reaction, also contains a number of genes which were activated in large follicles including IL6R, JNK, PIK3R and TSG6 (or TNFAIP6, already mentioned).
The evidence that the JAK/STAT pathway is activated in a large proportion of solid tumours and that its activation contributes to the malignant properties of cancer cells makes the JAK/STAT pathway a promising target for the development of new therapies.
It is involved in B-cell signaling through the CD40 receptor after activation of the RAS pathway [ 45] and was found to be activated in anaplastic large T-cell lymphomas [ 46].
c-Src non-receptor tyrosine kinase is overexpressed and activated in a large number of human malignancies and the relationship between activation and cancer progression appears significant (Irby and Yeatman, 2000).
Since PVD and FLP are also the largest neurons in worms with complicated dendritic arbor, we wondered if the UPR is particularly activated in these large cells.
It discusses that a set of brain areas, referred to as the pain-matrix is consistently activated in the large majority of the studies.
PDK1 is an important regulator of the PI3K/Akt pathway, which has been found frequently activated in a large number of human cancers.
