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In a wide variety of cancers, Akt is frequently over activated, contributing to malignancy and related with tumor aggressiveness [ 18].
As drug dependence develops, levels of the neurotransmitter dopamine decrease and the NE stress system in the brain is activated, contributing to "stress-like states" and increased vulnerability to stressors during periods of abstinence (Koob and Le Moal 2008).
Individuals may differ in the ease with which an analytical mode of processing can be activated (contributing to their trait tendency towards this form of rumination), but the level of analytical rumination at any given time (state level) may be dependent on immediate contextual factors.
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Protein kinase C (PKC), when activated, contributes to the propagation of some growth factors, including EGF and PDGF.
HER-2 (human epithelial receptor 2) is an example of an oncogene that, when activated, contributes to more aggressive behavior in breast cancers.
In a study analyzing mantle cell lymphoma growth caused by IL-22, Gelebart et al.[ 25] discovered that the gene promoter for IL-22Rα contained multiple binding sites for NF-κB, a transcription factor that when activated contributes to the pathogenesis and progressive loss of pancreatic β-cells by generating reactive oxygen species and promoting β-cell apoptosis.
Perhaps, the actual movement of one gene locus that becomes activated contributes to subsequent activation of other genes nearby.
Molecular dynamics simulations are performed to investigate the underlying thermally activated processes contributing to stress relaxation in a model binary amorphous system.
Scientists have shown that belief in, say, a potential painkiller's ability to reduce pain actually causes neural systems that modulate pain (e.g., opioids) to be activated, thus contributing to a placebo effect that in some people can be as effective as the drug itself.
On the other hand, how the FAK of tumor-associated cells resided within the tumor microenvironment activated and contributing to tumor progression is exploring in recent years.
By efficiently enhancing downstream signaling of HGF pathways, the cellular activities and behaviors were activated to contribute to LG branching morphogenesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com