The phrase "activated cleavage of" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in biochemistry or molecular biology, to describe a process where a cleavage event is triggered or initiated.
Example: "The activated cleavage of the protein was essential for the subsequent signaling cascade."
Alternatives: "triggered cleavage of" or "initiated cleavage of".
Instead, TRAIL activated cleavage of caspase-8 and caspase-3.
The most widely used approach currently exploits fluorescence to detect a 50 nm shift accompanying β-gal activated cleavage of DDAOG 7-hydroxy-9H- 1,3-dichloro-9,9-dimethylacridin-2-one-7-yll) β-D-galactopyranoside) revealing β-gal activity in stably transfected human tumors in mice following IV administration [24], [25].
Zhang, K. et al. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response.
The protein sites identified in this study enable the omptin to initiate activating cleavage of plasminogen but further substitutions are needed to stabilize plasmin.
Activating cleavage of the full length binding component occurs most likely between Lys209 and Leu210 to release a 20 kDa peptide and a 75 kDa peptide.
Also, Fas engagement can intersect with the intrinsic pathway through a caspase-8 activating cleavage of Bid – a Bcl-2 superfamily member that can trigger mitochondrial apoptosis.
A γ-secretase inhibitor, DAPT, which inhibits the activating cleavage of Notch receptors, reduced DCIS MFE from 0.88 ± 0.07% to 0.51 ± 0.08% (P = 0.0005).
We found that CHO-M2 cells were unable to activate cleavage of CA IX ECD, whereas CHO-WT and CHO-M2+TACE showed significantly increased shedding with both inducing factors, which was considerably reduced by BB-94.
By binding to TRAIL-R2, it activates cleavage of caspase-8 and caspase-3, which in turn cleaves and inactivates PPAR γ resulting in reduced expression of lipogenic genes, such as Glut-4, FASN, and ACC.
Presepsin, generated by circulating plasma proteases activating cleavage of soluble CD14 [ 18], is a novel biomarker that has been used for diagnosis of sepsis in recent years, and its production is associated with phagocytosis and cleavage of microorganisms by lysosomal enzymes [ 19].
In addition, activating cleavages of PARP and caspase 3 have been shown to be markedly increased in SPHK1-downregulated cells (Figure 2E).
