The phrase "activated by many" is correct and usable in written English.
It can be used to describe something that is triggered or initiated by a large number of people or entities.
Example: "The new software feature is activated by many users who opt in to the beta program."
Alternatives: "triggered by numerous" or "initiated by many".
PAR1 is the primary cell-surface receptor responsible for thrombin-mediated platelet aggregation in humans, but is also activated by many other proteases - including activated protein C (APC) and its receptor, the endothelial protein C receptor.
Signal transducer and activator of transcription 3 is known to be activated by many cytokines, growth factors and oncogenic proteins, and overexpression of activated (phosphorylated) p-STAT3 has been reported to be correlated with increased malignancy and a worse prognosis of patients with OSCC (Shinriki et al, 2009; Macha et al, 2011).
These retroviruses can be activated by many environmental factors, such as infections, ultraviolet (UV) light, hormones, stress and drugs [76].
It is well known that autophagy, a cellular stress response to degrade damaged components, can be activated by many nanoparticles.
Besides capsaicin, TRPV1 can be activated by many physical and chemical stimuli such as noxious heat (Caterina et al., 1997), low extracellular pH (Tominaga et al., 1998), divalent cations such as Mg2+ and Ba2+ (Yang et al., 2014; Cao et al., 2014; Ahern et al., 2005), as well as animal toxins (Bohlen et al., 2010; Siemens et al., 2006; Yang et al., 2015).
Akt is activated by many signaling pathways, such as overexpression of growth factor receptors, [40].
PI3K is activated by many signalling pathways, including the c-kit receptor [30].
Many cone genes are activated by Crx and many are repressed (in rods) by Nrl and Nr2e3 [13], [18] [20]]–[25], [25].
The catalytic subunit of CDKs is activated by one of many activating subunits, the cyclins.
Genes activated by STAT1 determine many of the functions related to the IFN/STAT1 pathway.
In those studies, nine of the 25 Tas2R bitter taste receptors were activated by quinine, while many other bitter compounds activate only one or a small number of receptors.
