Sentence examples for activated by large from inspiring English sources

The S6 segment, including Met1549, is virtually completely conserved (highlighted in yellow) among orthologs and all paralogs that are activated by small changes in membrane potential (l, low voltage-activated) but not those activated by large changes (h, high voltage-activated).

However, an activation of IK channels, another Ca2+-dependent K+ channel expressed in LNCaP cells activated by large increases in cytosolic Ca2+ concentration (Lallet-Daher et al., 2009; Parihar et al., 2003), was never observed in response to T-type Ca2+ channels activity.

The background seismicity rate estimated from a region activated by large earthquakes may produce apparent seismic quiescence accompanied by temporal decay, and vice versa.

Our analysis also included the sequences of the class A receptors which are naturally activated by large peptides that bind to their N-termini, such as glycoprotein hormone receptors (GPHRs).

This is especially true for 7TM receptors that are activated by large peptides or proteins, which bind to extracellular epitopes often including the N-terminus.

In contrast, CACNA1D, which is the most highly expressed calcium channel in adrenal cortex, and which shows larger single channel conductance than CACNA1H (Michels et al., 2002; Bock et al., 2011), is only activated by large depolarizations.

This channel is activated by larger depolarizing potentials and appears to have larger single channel conductance (Michels et al., 2002; Bock et al., 2011).

Yet another protein kinase, AMP-activated protein kinase (AMPK), is activated by a large variety of cellular stresses that deplete ATP and increase AMP, including glucose deprivation, hypoxia, ischaemia, oxidative stress and hyperosmotic stress [133].

Among the numerous inflammasome complexes, the NLRP3 inflammasome has been extensively studied and shown to be activated by a large variety of activators that do not share any structural similarities [ 3].

Despite the relative safety of CAR+ T-cell therapy in these studies, the risk remains that the hyper-physiologic activation of CAR+ T cells when synchronously activated by a large bio-burden of antigen-expressing cells could lead to toxicities resulting from systemic cytokine release, referred to as cytokine release syndrome [93], [96], [97], [100], [109].

The two divergent narrow pipes activated by a large reed would create a loud pungent sound highly prized by the Greeks.