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Moreover, it is known that Met is an inducible gene and that the promoter is activated by five Hypoxia Response Elements sensitive to HIF-1 α.
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An example for this case is a reaction transforming educt A into product B that can alternatively be activated by two activators E1 and E2.
Inflammasomes are activated by two major groups of activators, pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), which are potentially present in the tumour microenvironment of infection-associated cancers.
Similar to studies of the Xenopus laevis PXRs, the Xenopus tropicalis PXR was insensitive to steroids, vitamins, and xenobiotics that activate mammalian or chicken PXRs, but was activated by two benzoates described as activators of the Xenopus laevis PXRα (Additional File 5) [ 7, 49].
Membrane bound AKT is activated by two phosphorylations, by PDK1 at Thr-308 on the activation loop, and by mTORC2 at Ser-473 on the hydrophobic motif.
The E-P1 offers four different, redundant menu systems, activated by four confusingly similar buttons (labeled OK, Menu, Fn and Info).
DeWitt's Concept No. 3: X-Watch, described by the maker as "initially inspired from a concrete mixer," shows its mechanism in reverse and has an articulated X-shaped "bonnet," activated by four push-pieces, that partly covers its face.
Many involuntary muscles receive a double innervation, being activated by one type of nerve supply and inhibited by the other; modern experimentation indicates that the iris muscles are no exception, so that the sphincter has an inhibitory sympathetic nerve supply, while the dilator has a parasympathetic (cholinergic) inhibitor.
It yielded similar reaction products of the Nenitzescu reaction like other quinones activated by two electron-withdrawing groups.
The puppet is activated by four performers with Lady Godiva's head and eye movements being radio-controlled.
Thus, the system is activated by three quantities: stiffness and viscosity at the three joints among the three segments of the biped in Fig. 1.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com