The phrase "activated as a consequence" is correct and usable in written English.
It can be used to describe a situation where something is triggered or set in motion as a result of a specific event or condition.
Example: "The alarm system was activated as a consequence of the security breach."
Alternatives: "triggered as a result" or "initiated due to".
ERK1/2 may be activated as a consequence of aberrant activation of upstream signaling molecules or during development of drug resistance following treatment with kinase inhibitors such as those for PI3K or BRAF.
Consequently, our results suggested that MAPK15 may be activated as a consequence of ROS generation to stimulate autophagy, accelerating degradation of damaged mitochondria.
Upon TCR stimulation, Lck has been proposed to be activated as a consequence of PAG dephosphorylation and Csk release [12].
These results, like ours, support the notion that the Rac/Pak signaling axis is activated as a consequence of Merlin loss, and that these enzymes might provide useful targets for therapy in NF2.
We next used oxygen-and-glucose deprived (OGD) to simulate ischemic conditions and determine whether VRAC could be activated as a consequence of OGD treatment and the mechanism accounting for it.
As p19 is known not to bind to Raf1 [11] and therefore making it unlikely that p19 can activate ERK via Raf1, then it is reasonable to suggest that ERK1 may be activated as a consequence of increased levels of PKC that leads to phosphorylation of Raf1 as well as other signals acting on ERK1/2 in the MEK1/2 pathway [30].
By comparison, in other cancers, adaptation to hypoxia takes place during tumor progression when HIF1α is activated as a downstream consequence of oncogenic pathways.
Alternatively, the accumulation of DNA damage in histone chaperone-depleted cells might be the consequence of a prolonged replication slow down, since it was shown that neither ATM/Chk2 nor ATR/Chk1 are activated as an immediate consequence of histone deprivation but only after prolonged incubation times (>48 hr) (Mejlvang et al., 2014).
Then Akt/NF-kB pathway was activated, and as a consequence, the production of pro-inflammatory cytokines was enhanced.
This is consistent with JNK being activated indirectly as a consequence of disturbed cell polarity/morphology and further suggests that JNK alone might be sufficient for cooperation.
Synovial DCs were shown to be activated, probably as a consequence of proinflammatory signals derived from the RA joint environment, including cytokines and T-cell derived CD40 ligand [ 1, 2].
